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Alexis Brice Selected Research

Hypokinesia (Bradykinesia)

1/2011Large-scale screening of the Gaucher's disease-related glucocerebrosidase gene in Europeans with Parkinson's disease.
12/2009From genes to proteins in mendelian Parkinson's disease: an overview.

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Alexis Brice Research Topics

Disease

75Parkinson Disease (Parkinson's Disease)
04/2024 - 01/2002
34Spinocerebellar Ataxias (Spinocerebellar Ataxia)
04/2023 - 01/2002
20Parkinsonian Disorders (Parkinsonism)
04/2024 - 04/2002
16Frontotemporal Dementia (Semantic Dementia)
01/2023 - 07/2002
15Hereditary Spastic Paraplegia
11/2022 - 05/2002
14Cerebellar Ataxia (Dysmetria)
01/2022 - 07/2002
13Neurodegenerative Diseases (Neurodegenerative Disease)
12/2023 - 07/2002
12Cognitive Dysfunction
01/2024 - 08/2003
12Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
12/2021 - 07/2004
11Dementia (Dementias)
01/2023 - 08/2003
11Ataxia (Dyssynergia)
01/2023 - 02/2006
10Alzheimer Disease (Alzheimer's Disease)
12/2023 - 08/2002
10Disease Progression
01/2023 - 01/2016
10Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar)
02/2016 - 07/2008
7Atrophy
01/2021 - 07/2003
5Huntington Disease (Huntington's Disease)
06/2016 - 02/2002
5Tremor (Tremors)
04/2013 - 01/2009
4Disruptive, Impulse Control, and Conduct Disorders (Kleptomania)
01/2020 - 10/2016
4Paraplegia (Spastic Paraplegia)
12/2018 - 12/2004
4Movement Disorders (Movement Disorder)
10/2013 - 08/2003
3Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome)
12/2023 - 08/2012
3Intellectual Disability (Idiocy)
01/2023 - 01/2008
3Inborn Genetic Diseases (Disease, Hereditary)
01/2022 - 03/2006
3Dyskinesias (Dyskinesia)
01/2021 - 01/2011
3Mitochondrial Diseases (Mitochondrial Disease)
01/2019 - 05/2008
3Neoplasms (Cancer)
03/2017 - 05/2013
3Gaucher Disease (Gaucher's Disease)
11/2016 - 01/2011
3Epilepsy (Aura)
12/2014 - 04/2004
3Dopa-responsive Dystonia
09/2014 - 08/2003
3Dystonia (Limb Dystonia)
09/2014 - 08/2003
2Brain Diseases (Brain Disorder)
12/2023 - 01/2010
2Tourette Syndrome (Tourette's Syndrome)
01/2023 - 01/2019
2Inflammation (Inflammations)
10/2020 - 12/2014
2Lewy Body Disease (Lewy Body Dementia)
01/2020 - 06/2013
2Retinitis Pigmentosa (Pigmentary Retinopathy)
01/2020 - 12/2014
2Osteitis Deformans (Paget's Disease of Bone)
12/2018 - 01/2015
2Congenital, Hereditary, and Neonatal Diseases and Abnormalities (Congenital Disorders)
12/2017 - 12/2014
2Channelopathies
06/2017 - 11/2015
2Nervous System Diseases (Neurological Disorders)
03/2017 - 01/2017
2Pallidopyramidal syndrome
07/2015 - 04/2013
2Hypokinesia (Bradykinesia)
01/2011 - 12/2009
2autosomal dominant Spastic paraplegia 3
09/2009 - 12/2004
1Macular Degeneration (Age-Related Maculopathy)
12/2023
1Gait Ataxia
12/2023

Drug/Important Bio-Agent (IBA)

33Proteins (Proteins, Gene)FDA Link
01/2019 - 01/2002
22polyglutamineIBA
01/2018 - 01/2002
19Phosphotransferases (Kinase)IBA
04/2024 - 03/2006
16Leucine (L-Leucine)FDA Link
01/2019 - 09/2006
12Biomarkers (Surrogate Marker)IBA
01/2023 - 10/2012
12Levodopa (L Dopa)FDA LinkGeneric
01/2021 - 04/2002
12UbiquitinIBA
01/2016 - 01/2002
11ProgranulinsIBA
01/2021 - 04/2007
11Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA
01/2019 - 06/2003
8Ataxin-7IBA
11/2019 - 06/2002
8alpha-SynucleinIBA
01/2018 - 01/2002
7Dopamine (Intropin)FDA LinkGeneric
01/2018 - 07/2009
6Apolipoproteins E (ApoE)IBA
01/2024 - 07/2002
6tributyl phosphate (TBP)IBA
01/2023 - 07/2003
6Glucosylceramidase (Glucocerebrosidase)IBA
01/2020 - 01/2011
6SynucleinsIBA
01/2019 - 10/2011
5Amyloid (Amyloid Fibrils)IBA
01/2023 - 05/2003
5EnzymesIBA
01/2020 - 05/2003
5SpastinIBA
12/2018 - 08/2003
5Proteasome Endopeptidase Complex (Proteasome)IBA
08/2006 - 01/2002
3Carrier Proteins (Binding Protein)IBA
12/2023 - 05/2013
3Opioid Receptors (Opioid Receptor)IBA
01/2023 - 12/2018
3LipidsIBA
09/2019 - 09/2009
3Dihydroxyphenylalanine (Dopa)IBA
02/2016 - 08/2003
3Messenger RNA (mRNA)IBA
01/2016 - 02/2002
3CalciumIBA
11/2015 - 04/2005
3DNA (Deoxyribonucleic Acid)IBA
05/2015 - 06/2005
3Ligases (Synthetase)IBA
11/2009 - 01/2002
3protein kinase C gamma (PRKCG)IBA
06/2007 - 08/2004
3ApolipoproteinsIBA
07/2005 - 07/2002
2tau Proteins (tau Protein)IBA
12/2023 - 01/2016
2Ataxin-2IBA
04/2023 - 02/2007
2Mitochondrial DNA (mtDNA)IBA
01/2023 - 08/2014
2Dopamine Agonists (Dopamine Agonist)IBA
01/2020 - 12/2018
2indium arsenide (InAs)IBA
09/2018 - 11/2015
2GangliosidesIBA
01/2018 - 07/2013
2phosphomannomutaseIBA
12/2017 - 12/2014
2Congenital disorder of glycosylation type 1AIBA
12/2017 - 12/2014
2IronIBA
07/2015 - 07/2002
2FrataxinIBA
06/2015 - 07/2002
2NucleotidesIBA
02/2015 - 11/2010
2DNA-Binding Proteins (DNA Binding Protein)IBA
11/2014 - 04/2009
2GTP Cyclohydrolase (GTP Cyclohydrolase I)IBA
09/2014 - 08/2003
2Guanosine Triphosphate (GTP)IBA
09/2014 - 07/2009
2preproenkephalinIBA
07/2013 - 03/2002
2Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA
08/2012 - 04/2009
2sepiapterin reductaseIBA
11/2011 - 07/2009
2Brain-Derived Neurotrophic Factor (BDNF)IBA
08/2011 - 03/2002
2Tyrosine 3-Monooxygenase (Tyrosine Hydroxylase)IBA
07/2009 - 03/2002
2CholesterolIBA
05/2008 - 02/2005
2TATA-Box Binding Protein (TATA-Binding Protein)IBA
01/2008 - 07/2003
1rab GTP-Binding ProteinsIBA
04/2024

Therapy/Procedure

14Therapeutics
01/2023 - 02/2011
2Deep Brain Stimulation
01/2020 - 02/2016
2Denervation
05/2015 - 09/2014
2Ligation
05/2014 - 10/2012